二丁酸雌二醇
 | |
| 臨床資料 | |
|---|---|
| 其他名稱 | EDBu; Estradiol dibutanoate; Estradiol 3,17β-dibutanoate |
| 給藥途徑 | Intramuscular injection |
| 藥物類別 | Estrogen; Estrogen ester |
| 識別資訊 | |
| CAS號 | 63042-23-9  |
| ChemSpider | |
| UNII | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.057.990 |
| 化學資訊 | |
| 化學式 | C26H36O4 |
| 摩爾質量 | 412.57 g·mol−1 |
| 3D模型（JSmol） | |
| |
| |
二丁酸雌二醇（英語：Estradiol dibutyrate或Estradiol dibutanoate），或名雌二醇二丁酸酯，是一種雌激素藥物和一種雌激素酯，具體來說雌二醇的二酯，該藥物現已不再使用。[1][2]它是Triormon Depositum的一個成分，該藥物是1950年代開發的由二丁酸雌二醇、己酸睪酮和庚酸羥孕酮的組合配方。[2]
參見
[編輯]- 雌激素酯列表
- 二丁酸雌二醇/庚酸羥孕酮/己酸睪酮（商品名為Triormon Depositum）
參考資料
[編輯]- ^ Cacciari P. [Experimental research on estradiol dibutyrate]. Minerva Ginecol. August 1960, 12: 788–9. PMID 13689684 （義大利語）.
- ^ 2.0 2.1 Ermiglia, G; Valli, P. Triormon depositum in climacteric syndrome. Curves of excretion of catabolites and duration of the therapeutic effect. Quaderni Clin. Ostet. E Ginecol. 1957, 12: 284–93.
Triormon depositum (estradiol dibutyrate 3, testosterone caprylate 50, and hydroxyprogesterone heptanoate 30 mg.), administered in castor oil-benzyl benzoate soln. or polyvinylpyrrolidone suspension to 21 women in climacteric, was followed by estradiol, pregnanediol, and 17-keto steroid urinary curves, most with a peak at the 4th day, and approaching starting values at the 8-10th day. The therapeutic efficacy of the drug was satisfactory.