二丁酸雌二醇
 | |
| 临床资料 | |
|---|---|
| 其他名称 | EDBu; Estradiol dibutanoate; Estradiol 3,17β-dibutanoate |
| 给药途径 | Intramuscular injection |
| 药物类别 | Estrogen; Estrogen ester |
| 识别信息 | |
| CAS号 | 63042-23-9  |
| ChemSpider | |
| UNII | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.057.990 |
| 化学信息 | |
| 化学式 | C26H36O4 |
| 摩尔质量 | 412.57 g·mol−1 |
| 3D模型（JSmol） | |
| |
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二丁酸雌二醇（英语：Estradiol dibutyrate或Estradiol dibutanoate），或名雌二醇二丁酸酯，是一种雌激素药物和一种雌激素酯，具体来说雌二醇的二酯，该药物现已不再使用。[1][2]它是Triormon Depositum的一个成分，该药物是1950年代开发的由二丁酸雌二醇、己酸睾酮和庚酸羟孕酮的组合配方。[2]
参见
[编辑]- 雌激素酯列表
- 二丁酸雌二醇/庚酸羟孕酮/己酸睾酮（商品名为Triormon Depositum）
参考资料
[编辑]- ^ Cacciari P. [Experimental research on estradiol dibutyrate]. Minerva Ginecol. August 1960, 12: 788–9. PMID 13689684 （意大利语）.
- ^ 2.0 2.1 Ermiglia, G; Valli, P. Triormon depositum in climacteric syndrome. Curves of excretion of catabolites and duration of the therapeutic effect. Quaderni Clin. Ostet. E Ginecol. 1957, 12: 284–93.
Triormon depositum (estradiol dibutyrate 3, testosterone caprylate 50, and hydroxyprogesterone heptanoate 30 mg.), administered in castor oil-benzyl benzoate soln. or polyvinylpyrrolidone suspension to 21 women in climacteric, was followed by estradiol, pregnanediol, and 17-keto steroid urinary curves, most with a peak at the 4th day, and approaching starting values at the 8-10th day. The therapeutic efficacy of the drug was satisfactory.