鄰苯二甲酸單苄酯
| 鄰苯二甲酸單苄酯 | |
|---|---|
| |
| IUPAC名 2-phenylmethoxycarbonylbenzoic acid[1] | |
| 別名 | Phthalic Acid Monobenzyl Ester[1] Benzyl hydrogen phthalate[1] 1,2-Benzenedicarboxylic acid, mono(phenylmethyl) ester[1] Mono(phenylmethyl) 1,2-benzenedicarboxylate[1] 2-phenylmethoxycarbonylbenzoic acid[1] |
| 識別 | |
| CAS號 | 2528-16-7 |
| PubChem | 31736 |
| ChemSpider | 29430 |
| SMILES |
|
| ChEBI | 132612 |
| 性質 | |
| 化學式 | C15H12O4 |
| 摩爾質量 | 256.25 g·mol−1 |
| 危險性 | |
GHS危險性符號
| |
| GHS提示詞 | Warning |
| H-術語 | H319 |
| P-術語 | P264, P280, P305+351+338, P337+313 |
| 若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。 | |
鄰苯二甲酸單苄酯（英語：Monobenzyl phthalate，縮寫MBzP，IUPAC名為2-苯甲氧基羰基苯甲酸，2-phenylmethoxycarbonylbenzoic acid）是一種結構簡式為C6H5CH2OOCC6H4COOH的有機化合物。MBzP為鄰苯二甲酸丁苄酯在人體內的主要初級代謝產物，多於另一種水解產物鄰苯二甲酸單丁酯 (MBP)[2][3]。和其它許多鄰苯二甲酸酯一樣，MBzP也是一種內分泌干擾物[4][5]。
參考文獻
[編輯]- ^ 1.0 1.1 1.2 1.3 1.4 1.5 Monobenzyl phthalate. PubChem. National Center for Biotechnology Information, U.S. National Library of Medicine. February 29, 2020 [March 5, 2020]. （原始內容存檔於2020-08-03）.
- ^ Huang, Jingyu; Nkrumah, Philip N.; Li, Yi; Appiah-Sefah, Gloria. Chemical Behavior of Phthalates Under Abiotic Conditions in Landfills. Reviews of Environmental Contamination and Toxicology 224. New York, NY: Springer Science+Business Media. 2013: 39–52. ISBN 9781461458814. PMID 23232918. doi:10.1007/978-1-4614-5882-1_2.
- ^ Saillenfait AM, Sabaté JP, Gallissot F. Comparative embryotoxicities of butyl benzyl phthalate, mono-n-butyl phthalate and mono-benzyl phthalate in mice and rats: in vivo and in vitro observations. Reproductive Toxicology. 2002, 17 (5): 575–83. PMID 14555196. doi:10.1016/s0890-6238(03)00102-3.
- ^ Ema M, Harazono A, Miyawaki E, Ogawa Y. Developmental toxicity of mono-n-benzyl phthalate, one of the major metabolites of the plasticizer n-butyl benzyl phthalate, in rats. Toxicology Letters. July 1996, 86 (1): 19–25. PMID 8685916. doi:10.1016/0378-4274(96)03665-x.
- ^ Ema M, Harazono A, Miyawaki E, Ogawa Y. Characterization of developmental toxicity of mono-n-benzyl phthalate in rats. Reproductive Toxicology. 1995, 10 (5): 365–72. PMID 8888408. doi:10.1016/0890-6238(96)00082-2.