2-氟-6-氯苄胺
| 2-氟-6-氯苄胺 | |
|---|---|
| |
| 别名 | 2-氯-6-氟苄胺 2-氟-6-氯苯甲胺 |
| 识别 | |
| CAS号 | 15205-15-9 
|
| 性质 | |
| 化学式 | C7H7ClFN |
| 摩尔质量 | 159.59 g·mol−1 |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
2-氟-6-氯苄胺是一种有机化合物，化学式为C7H7ClFN，它可用于合成氟腺呤以及含2-氟-6-氯苯基的𫫇唑类PDE4抑制剂。[1][2]它可由2-氟-6-氯苯甲腈的还原反应制得。[3]
参考文献
[编辑]- ^ Merck & Co. R. J. Tull, G. D. Hartman, and L. M. Weinstock, U.S. Patent 4,098,787 (1978).
- ^ Rongze Kuang, Ho-Jane Shue, Li Xiao, David J. Blythin, Neng-Yang Shih, Xiao Chen, Danlin Gu, John Schwerdt, Ling Lin, Pauline C. Ting, Jianhua Cao, Robert Aslanian, John J. Piwinski, Daniel Prelusky, Ping Wu, Ji Zhang, Xiang Zhang, Chander S. Celly, Motasim Billah, Peng Wang. Discovery of oxazole-based PDE4 inhibitors with picomolar potency. Bioorganic & Medicinal Chemistry Letters. 2012-04, 22 (7): 2594–2597 [2021-12-21]. doi:10.1016/j.bmcl.2012.01.115. （原始内容存档于2020-02-13） （英语）.
- ^ Steven Holshouser, Matthew Dunworth, Tracy Murray-Stewart, Yuri K. Peterson, Pieter Burger, Joy Kirkpatrick, Huan-Huan Chen, Robert A. Casero, Patrick M. Woster. Dual inhibitors of LSD1 and spermine oxidase. MedChemComm. 2019, 10 (5): 778–790 [2021-12-21]. ISSN 2040-2503. PMC 6533887
. PMID 31191868. doi:10.1039/C8MD00610E （英语）.
