1,4-二氢吡啶

1,4-二氢吡啶
	系统名; 1,4-Dihydropyridine
识别
CAS号	3337-17-5
PubChem	104822
ChemSpider	94619
SMILES	C1C=CNC=C1;
MeSH	1,4-dihydropyridine
性质
化学式	C; 5H; 7N
摩尔质量	81.1158 g mol−1 g·mol⁻¹
密度	0.910±0.06 g·cm−3
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

1,4-二氢吡啶（英語：1,4-Dihydropyridine，缩写DHP）是一种不稳定的有机化合物，化学式为C₅H₇N，其零点振动能为0.1125 Ha^[3]。它可由1-三甲基硅基-1,4-二氢吡啶和甲醇反应^[4]，或吡啶和氢化铝锂反应^[5]得到，后者会同时产生其它二氢吡啶的异构体。

参考文献

^ 1,4-dihydropyridine - Compound Summary. Pubchem Compound. USA: National Center for Biotechnology Information. Identification and Related Records. 27 March 2005 [1 November 2011]. （原始内容存档于2012-10-11）.
^ Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2019 ACD/Labs). Retrieved from SciFinder. [2019-11-14]
^ Lan-Fen Wang, Hong-Yu Zhang, Ling Kong, Zhi-Wei Chen, Jian-Guo Shi. DFT Calculations Indicate that 1,4-Dihydropyridine Is a Promising Lead Antioxidant. Helvetica Chimica Acta. 2004-06, 87 (6): 1515–1521 [2019-11-14]. ISSN 0018-019X. doi:10.1002/hlca.200490138 （英语）.
^ Newell C. Cook, James E. Lyons. 1,4-Dihydropyridine. Journal of the American Chemical Society. 1965-07, 87 (14): 3283–3284 [2019-11-14]. ISSN 0002-7863. doi:10.1021/ja01092a074 （英语）.
^ Arthur J. Birch, Edouard A. Karakhanov. Preparation of some N-substituted 1,4-dihydropyridines by metal–ammonia reactions. J. Chem. Soc., Chem. Commun. 1975, (12): 480–481 [2019-11-14]. ISSN 0022-4936. doi:10.1039/C39750000480 （英语）.

参见

伯奇还原反应

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[1] 1,4-dihydropyridine - Compound Summary. Pubchem Compound. USA: National Center for Biotechnology Information. Identification and Related Records. 27 March 2005 [1 November 2011]. （原始内容存档于2012-10-11）.

[2] Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2019 ACD/Labs). Retrieved from SciFinder. [2019-11-14]

[3] Lan-Fen Wang, Hong-Yu Zhang, Ling Kong, Zhi-Wei Chen, Jian-Guo Shi. DFT Calculations Indicate that 1,4-Dihydropyridine Is a Promising Lead Antioxidant. Helvetica Chimica Acta. 2004-06, 87 (6): 1515–1521 [2019-11-14]. ISSN 0018-019X. doi:10.1002/hlca.200490138 （英语）.

[4] Newell C. Cook, James E. Lyons. 1,4-Dihydropyridine. Journal of the American Chemical Society. 1965-07, 87 (14): 3283–3284 [2019-11-14]. ISSN 0002-7863. doi:10.1021/ja01092a074 （英语）.

[5] Arthur J. Birch, Edouard A. Karakhanov. Preparation of some N-substituted 1,4-dihydropyridines by metal–ammonia reactions. J. Chem. Soc., Chem. Commun. 1975, (12): 480–481 [2019-11-14]. ISSN 0022-4936. doi:10.1039/C39750000480 （英语）.

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