龙脑香醇酮

龙脑香醇酮
英文名	Dipterocarpol
别名	20-羟基达玛-24-烯-3-酮
识别
CAS号	471-69-2
PubChem	441676
ChemSpider	390290
SMILES	CC(=CCCC(C)(C1CCC2(C1CCC3C2(CCC4C3(CCC(=O)C4(C)C)C)C)C)O)C;
InChI	InChI=1S/C30H50O2/c1-20(2)10-9-16-30(8,32)22-13-18-28(6)21(22)11-12-24-27(5)17-15-25(31)26(3,4)23(27)14-19-29(24,28)7/h10,21-24,32H,9,11-19H2,1-8H3/t21-,22+,23+,24-,27+,28-,29-,30+/m1/s1;
InChIKey	NJICGAVMYWKCMW-GWJXCKMPSA-N
ChEBI	4652
性质
化学式	C30H50O2
摩尔质量	442.72 g·mol−1
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

龙脑香醇酮（英語：Dipterocarpol），别名羟基达玛烯酮II（英語：Hydroxydammarenone II），是一种有机化合物，化学式C₃₀H₅₀O₂，可见于Dysoxylum malabaricum（英语：Dysoxylum malabaricum）^[1]、鸦胆子^[2]等物种。它是麝香心痛宁及复方丹参滴丸的生物活性组分之一。^[3]^[4]

它可以羟基藿烷酮为原料经多步反应制得。^[5]

参考资料

^ Hisham A; Bai A; JayaKumar G; Nair MS; Fujimoto Y. Triterpenoids from Dysoxylum malabaricum.. Phytochemistry. 2001-02, 56 (4). doi:10.1016/S0031-9422(00)00413-1.
^ Tzong-Huei Lee; Jong-Liang Chiou; Ching-Kuo Lee; Yueh-Hsiung Kuo. Separation and Determination of Chemical Constituents in the Roots ofRhus JavanicaL. Var.Roxburghiana. Journal of the Chinese Chemical Society. 2005-08, 52 (4). doi:10.1002/JCCS.200500117.
^ Xiaohong Wang; Jiawei Zhou; Tianlin Jiang; Jun Xu. Deciphering the therapeutic potential of SheXiangXinTongNing: Interplay between gut microbiota and brain metabolomics in a CUMS mice model, with a focus on tryptophan metabolism. Phytomedicine, 2024. 129. 155584. doi:10.1016/j.phymed.2024.155584.
^ Tian, Xiaocui; Yin, Shiqi; Liu, Zhiguang; Cao, Jinglin; Liu, Xinyu; Qiu, Qi. Elucidation of the Molecular Mechanism of Compound Danshen Dripping Pills against Angina Pectoris based on Network Pharmacology and Molecular Docking. Current Pharmaceutical Design (2024), 30(16), 1247-1264. doi:10.2174/0113816128287109240321074628.
^ Ryoji Kasai; Keiko Shinzo; Osamu Tanaka. Syntheses of Betulafolienetriol and the Ginseng Sapogenin, 20 (S)-Protopanaxadiol. Chemical and Pharmaceutical Bulletin, 1976. 24 (3). doi:10.1248/cpb.24.400.

这是一篇关于有机化合物的小作品。您可以通过编辑或修订扩充其内容。

[1] Hisham A; Bai A; JayaKumar G; Nair MS; Fujimoto Y. Triterpenoids from Dysoxylum malabaricum.. Phytochemistry. 2001-02, 56 (4). doi:10.1016/S0031-9422(00)00413-1.

[2] Tzong-Huei Lee; Jong-Liang Chiou; Ching-Kuo Lee; Yueh-Hsiung Kuo. Separation and Determination of Chemical Constituents in the Roots ofRhus JavanicaL. Var.Roxburghiana. Journal of the Chinese Chemical Society. 2005-08, 52 (4). doi:10.1002/JCCS.200500117.

[3] Xiaohong Wang; Jiawei Zhou; Tianlin Jiang; Jun Xu. Deciphering the therapeutic potential of SheXiangXinTongNing: Interplay between gut microbiota and brain metabolomics in a CUMS mice model, with a focus on tryptophan metabolism. Phytomedicine, 2024. 129. 155584. doi:10.1016/j.phymed.2024.155584.

[4] Tian, Xiaocui; Yin, Shiqi; Liu, Zhiguang; Cao, Jinglin; Liu, Xinyu; Qiu, Qi. Elucidation of the Molecular Mechanism of Compound Danshen Dripping Pills against Angina Pectoris based on Network Pharmacology and Molecular Docking. Current Pharmaceutical Design (2024), 30(16), 1247-1264. doi:10.2174/0113816128287109240321074628.

[5] Ryoji Kasai; Keiko Shinzo; Osamu Tanaka. Syntheses of Betulafolienetriol and the Ginseng Sapogenin, 20 (S)-Protopanaxadiol. Chemical and Pharmaceutical Bulletin, 1976. 24 (3). doi:10.1248/cpb.24.400.

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